Chicago Bears and Buffalo Bills have played a total of 14 games against each other, including the regular season and playoffs. The Bears have won 8 of these games, while the Bills have won 6 times. No games between the Bears and Bills ended in ties. The Bears and Bills are yet to face each other in the playoffs.
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Chicago Bears vs Buffalo Bills Head To Head Records & Stats
| Event | Games | Chicago Bears Won | Buffalo Bills Won | Ties |
| NFL Regular Season | 14 | 8 | 6 | 0 |
| NFL Playoffs | 0 | 0 | 0 | 0 |
| Overall | 14 | 8 | 6 | 0 |
Chicago Bears vs Buffalo Bills H2H Longest Winning Streaks
The longest winning streak for the Chicago Bears over the Buffalo Bills is 2 games. The latest streak started on 8 October 2006 and lasted till 7 November 2010. On the other hand, the longest winning streak for the Buffalo Bills over the Chicago Bears is 2 games. The streak started on 12 November 2000 and ended on 29 September 2002.
Chicago Bears vs Buffalo Bills: Last 10 Games Results
| Date | Home Team | Visiting Team | Winning Team | Final Score |
| 12/24/2022 | Chicago Bears | Buffalo Bills | Buffalo Bills | 13-35 |
| 11/04/2018 | Buffalo Bills | Chicago Bears | Chicago Bears | 9-41 |
| 09/07/2014 | Chicago Bears | Buffalo Bills | Buffalo Bills | 20-23 |
| 11/07/2010 | Buffalo Bills | Chicago Bears | Chicago Bears | 19-22 |
| 10/08/2006 | Chicago Bears | Buffalo Bills | Buffalo Bills | 40-7 |
| 09/29/2002 | Buffalo Bills | Chicago Bears | Buffalo Bills | 33-27 |
| 11/12/2000 | Buffalo Bills | Chicago Bears | Chicago Bears | 20-3 |
| 12/07/1997 | Chicago Bears | Buffalo Bills | Chicago Bears | 20-3 |
| 10/02/1994 | Chicago Bears | Buffalo Bills | Chicago Bears | 20-13 |
| 09/29/1991 | Buffalo Bills | Chicago Bears | Buffalo Bills | 35-20 |
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